In seven studies related to FGFR, five reported FGFR3 alterations,68, 69, 70, 71, 72 one explored FGFR family alterations in UC patients,73 and one investigated the landscape of FGF/FGFR alterations in a large cohort of 12,737 cancer patients with a high prevalence of FGF/FGFR mutations occurring in urinary tract cancer (52.7%, 145/275).74 The gene discussed is FGFR3; the disease is cancer.