A high level of STEAP3 expression supports the proliferation of numerous cancer cells by stimulating iron uptake and preserving iron storage, including glioblastoma [17], hepatocellular carcinoma [18], bladder cancer [19], colorectal cancer [20], etc. Despite the significance of the STEAP gene family in tumorigenesis and development, comprehensive analyses of the importance of STEAP3 in OC remain insufficient. The gene discussed is STEAP3; the disease is urinary bladder cancer.