CEACAM5 and colorectal carcinoma: Although the AUC values among miR-185-5p (0.700), CA199 (0.677, P = 0.8388), and CEA (0.626, P = 0.4933) for the diagnosis of I-II stage CRC vs. AA were similar, the diagnostic sensitivity of miR-185-5p (75.86%) was not significantly lower than that of CA199 (79.31%) and was higher than that of CEA (51.72%) (Additional file 5: Fig. S5A-S5C).