The results showed that the P values of SLC25A17 expression level (HR uni-Cox: 1.602, HR multi-Cox: 1.520), age (HR uni-Cox: 1.020, HR multi-Cox: 1.024) and lymph node metastasis (HR uni-Cox: 1.553, HR multi-Cox: 1.374) were all less than 0.05 and could be used as independent prognostic factors. This evidence concerns the gene SLC25A17 and metastatic malignant neoplasm in the lymph nodes.