Other significant genes identified in rare variant gene-based association analysis included FKBP9, LTBP2, COL2A1 and the well-known glaucoma gene MYOC. We found that FKBP9 is 400 kb from the common SNP rs1544557 in the POAG MTAG GWAS, LTBP2 is 20 kb from the common POAG SNP rs754634 and COL2A1 is associated with VCDR (lead SNP rs12821310)8. Here, LTBP2 is linked to glaucoma.