TNF and Behcet disease: The purpose of this work is to analyze and characterize the local and systemic participation of immunologic response in an experimental model of BD, though evaluation of TNF-α, IL-1β, IL-6, IL-10, the quantification of macrophages, NF-κB activity in hepatic tissue, liver allogenicity, and, evaluate liver biochemistry parameters by determining plasma levels of AST, ALT, LDH and ALF in patient with and without BD.