In particular, VIL1, participating in the organization of the microvillar cytoskeleton and the structure of the brush border [48], and LIMA1, a tumor suppressor [49] involved in the formation of cadherin-catenin complex’s interaction with the cytoskeleton and acting as a mechanosensitive regulator in the preservation of the apical-basal polarity [50]. Here, LIMA1 is linked to neoplasm.