Moreover, lung cancer patients with high expressions of IL-6 (Fig. 6B), Panx1 (Fig. 6C), or both IL-6 and Panx1 (Fig. 6D) genes were associated with poorer overall survival than those having low expression levels of IL-6, Panx1, or both IL-6 and Panx1, respectively. This evidence concerns the gene PANX1 and lung cancer.