Although neurological and kidney involvement is rare, class III and IV lupus nephritis and less commonly class V are more often seen in EIL than in other DIL.3,4 Induction of autoantibodies (ANA and anti–ds-DNA) has been observed in patients receiving anti-TNFα agents.1,3 The presumed mechanism is induction of apoptosis promoting antibody production against uncleared antigenic nucleosomes.5 The diagnosis of TAILS is based on history and clinical features. Here, TNF is linked to lupus nephritis.