Furthermore, in a receiver operating characteristic (ROC) curve analysis, MUC4 rs1104760 A>G was indicated as a possible biomarker for CRC patients with high LDL-C levels (area under the curve (AUC) = 0.689) compared to those with normal LDL-C levels (AUC = 0.603) (Fig 2). The gene discussed is MUC4; the disease is colorectal carcinoma.