To explore the clinical relevance of RBPs mRNA expression (upregulation vs. downregulation) in COREAD, COAD, and READ patients, we have interrogated TCGA, PanCancer Atlas (Hoadley et al., 2018) database for mRNA expression of prioritized RBPs (NAT10, NOP56, RBM12, FKBP1A, CSE1L, and EMG1) in those populations and calculated several clinical aspects (OS and DFS). This evidence concerns the gene RBM12 and reading.