RET and non-small cell lung carcinoma: According to the Global Oncology Trends 2021, 17 new oncology therapeutic drugs were launched in 2020 alone for 22 different applications with capmatinib being the first therapy approved for targeting metastatic non-small cell lung cancer (NSCLC) with mesenchymal-epithelial transition (MET) exon 14 skipping while both pralsetinib and selpercatinib approved for rearranged during transfection (RET)-altered NSCLC (IQVIA, 2021).