Although in our study the incidence of TERT promoter gene mutation in two groups of malignant and benign salivary gland tumors was not statistically different (P>0.05), This study can serve as a guide in the field of genetic-molecular studies on malignant salivary gland tumors with a higher statistical population. The gene discussed is TERT; the disease is benign neoplasm of salivary gland.