The expression levels of Cleaved‐Caspase3 and Bax were significantly increased, and Bcl‐2 levels were decreased, in adriamycin‐induced nephropathy rats, while PA and EPI could decrease the levels of Cleaved‐Caspase3 and Bax and increase the levels of Bcl‐2 (Figure 8D). This evidence concerns the gene BCL2 and kidney disorder.