CXCR5 and rheumatoid arthritis: The methylation level of CXCR5 was significantly higher in rheumatoid arthritis(RA) patients than in osteoarthritisand HC, and correlated with the level of inflammation in RA patients, Our study establishes a link between CXCR5 DNA methylation and clinical features that may help in the diagnosis and disease management of RA patients.