Recent studies have shown that IL‐38 could inhibit the activation of intracellular STAT1/3, ERK1/2, P38 MAPK, and NF‐κB signaling pathways, and upregulate the expression of antiallergic response gene RGS13 and host defense‐related gene POU2AF1 in mice with allergic asthma.32 This evidence concerns the gene STAT1 and allergic asthma.