Instead, TP53RK bound to and phosphorylated Birc5 at Thr34 and mediated colon cancer metastasis.[11] In line with this reference, we overexpressed and knocked down TP53RK in mPTCs and found no influence on p53 phosphorylation on Ser15 (Figure S7, Supporting Information). The gene discussed is TP53; the disease is malignant colon neoplasm.