The expression of TP53RK was then examined in kidneys of UUO, and unilateral ischemia reperfusion (UIR) murine models, of which UUO is a well‐known model of kidney injury accompanied by progressive tubulointerstitial fibrosis and UIR recapitulates the process of acute kidney injury (AKI)–CKD transition. The gene discussed is TP53RK; the disease is acute kidney injury.