The top 25 KEGG pathways included Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, MAPK signaling pathway, mTOR signaling pathway, NF-κB signaling pathway, JAK-STAT signaling pathway, and Pathways in cancer (Fig. 4C). Here, TNF is linked to cancer.