A total of 7 individual brain tumor reports (GSE30074: medulloblastoma, GSE16581: meningioma, GSE28026: atypical teratoid/rhabdoid tumors, GSE4271: high-grade astrocytomas, GSE4412: gliomas, GSE13041 and GSE7696: GBM) were collected, and the forest plot of the hazard ratio of ISG20 with OS in brain tumor patients is shown in Fig. 3. Here, ISG20 is linked to central nervous system cancer.