DPYSL3 and metastatic malignant neoplasm in the lymph nodes: In patients with UBUC, increased expression of DPYSL3 was frequently related to muscle-invasive bladder cancer (MIBC) (p < 0.001), lymph node metastasis (p = 0.012), vascular invasion (p < 0.001), and perineural invasion (p = 0.021).