The down-regulated expression levels of MTF1 could be identified in most of cancers, including breast invasive carcinoma (BRCA), COAD, kidney chromophobe (KICH), KIRC, kidney renal papillary cell carcinoma (KIRP), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), thyroid carcinoma (THCA), uterine corpus endometrial carcinoma (UCEC), bladder urothelial carcinoma (BLCA) and rectum adenocarcinoma (READ). This evidence concerns the gene MTF1 and chromophobe renal cell carcinoma.