In addition, the promoter methylation levels of MTF1 in primary tumor group from prostate adenocarcinoma (PRAD, p = 1.46826995006677E-12), BLCA (p = 1.017200E-03), head and neck squamous cell carcinoma (HNSC, p = 4.837900E-03) and UCEC (p = 3.52490259203364E-11) were lower than that in the normal groups (Supplementary Figure S6N-Q). The gene discussed is MTF1; the disease is bladder transitional cell carcinoma.