We previously reported significant elevation of plasma protein levels of six different type I, II, and III IFNs in patients with COVID-19 (IFNA1, IFNA2, IFNA4/16, IFNA6, IFNG, and IFNL3/2) and that IFN scores are associated mostly with levels of IFNA2 and IFNG in COVID-19 (22). The gene discussed is IFNG; the disease is COVID-19.