Stop-gain variant NM_015693.4:c.581G>A in INTU in the Hedgehog signalling pathway and stop-gain variant NM_000288.4:c.875T>A in PEX7 in peroxisomal pathway each segregated with lymphoid cancers in families, suggesting that these variants in these genes may be related to risk of lymphoid cancer. Here, PEX7 is linked to lymphoma.