Expression analysis revealed that 11 genes (MYC, CASP3, CBL, RB1, MAD2L1, PLCG1, CHEK1, FBXW7, NUP155, RAN and DDX55) and 7 genes (RHOA, FMR1, SUPT16H, CALM1, CTCF and UBXN7) were significantly upregulated and downregulated in ccRCC when compared with normal controls, respectively. This evidence concerns the gene RAN and nonpapillary renal cell carcinoma.