Survival analysis showed that 8 genes (RHOA, CASP3, MAD2L1, PLCG1, CHEK1, FBXW7, RAN and DDX55) and 11 genes (NCL, FMR1, AGO1, DDX3X, SUPT16H, CBL, RB1, CALM1, NUP155, CTCF and UBXN7) indicated poor and good prognosis in ccRCC patients, respectively. The gene discussed is DDX3X; the disease is nonpapillary renal cell carcinoma.