Based on the number of genes and the fold change of expression, the largest difference in DEGs was observed 24 h after stroke, where the 10 top most upregulated genes included the following: interleukin 11 (Il11), interleukin 6 (Il6), retinol dehydrogenase 10 (Rdh10), endothelin receptor B (Ednrb), C-C motif chemokine ligand 2 (Ccl2), metallothionein-2 (Mt2), stanniocalcin 1 (Stc1), ADAM metallopeptidase with thrombospondin type 1 motif 4 (Adamts4), drebrin 1 (Dbn1), and follistatin like 1 (Fstl1) (Fig. 3e). This evidence concerns the gene ADAMTS4 and Stroke.