Univariate analysis demonstrated that a higher Killip class was negatively associated with HPA (OR = 0.35: 95% CI, 0.24–0.50; p < 0.001), which remained significant following multivariate adjustment for sociodemographic factors (age, sex, smoking, and alcohol consumption) and clinical demographic factors (hypertension, diabetes, family history of MI, interventional therapy, BMI, and cTnT) (adjusted OR = 0.48: 95% CI, 0.32–0.71; p < 0.001). The gene discussed is TNNT2; the disease is hypertensive disorder.