In conclusion, Ahsg, Bpgm, Litaf, Acsm2, Hadha, Keg1, Sh3glb1, Eif3d, Ambp, and Ddah2 were identified as potential biomarkers of AKI caused by EHS, which may help in the future in the clinical management and prognosis of patients, even if our study does not provide direct help for clinical application. Here, ACSM2A is linked to acute kidney injury.