Loci rs2233977, rs20547, rs1063646, rs9263719, rs3094663, rs6916921, rs3819299 and rs12614 are mapped to C6orf15, PSMB9, PSORS1C1, PSORS1C2, NFKBIL1, HLA-B and CFB genes which are associated with RA (52–54). Here, CFB is linked to rheumatoid arthritis.