NFKBIZ and psoriasis: IκBζ is a direct transcription activator of psoriasis-related genes; the single-nucleotide polymorphism (SNP) rs7637230 in NFKBIZ (position 101663555) is related to psoriasis mobility, and an adenine in this SNP increases the risk of developing psoriasis compared with the risk associated with guanine (OR=1.14) in individuals of European descent (123).