Meanwhile, ten key hub genes (AHNAK2, GPC2, DBNDD2, OLFM1, SCRG1, TNFAIP8L2, FILIP1L, CYSTM1, PARM1, and NCAPG) are determined using the Friend analysis, which is associated with the prognosis of STS. This evidence concerns the gene OLFM1 and telomere syndrome.