MYC and neoplasm: In addition, pathway analysis revealed that tumor-associated pathways such as TGF-β and Wnt-β catenin signaling, cell cycle-related pathways such as MYC, and immune-related pathways such as inflammatory response and IL2-STAT5 signaling were distinctly enriched in CSC1 and CSC2, which was responsible for their different anti-cancer response and prognosis.