lncRNA ZEB1-AS1 high expression was correlated with poor prognosis in COAD, and ZEB1-AS1 acted as a sponge in adsorbing to miR-455-3p and bound to it to regulate COAD cell growth and metastasis by targeting the action of PAK2 (Ni et al., 2020). This evidence concerns the gene ZEB1 and colon adenocarcinoma.