Fatigue, Diarrhoea, Oral mucositis,AST increase, ALT increase,Palmar-plantar syndrome, Thrombocytopenia, Hypophosphataemia, Neutropenia,Hypomagnesaemia, Anaemia,Lipase increased, Pneumothorax,Leucopenia, Hypertension. This evidence concerns the gene GPT and hypertensive disorder.