ETV6 and blood platelet disease: ETS TFs (e.g. ETS1, ETS2, ELF1, ERG, ETV2, ETV6, FEV, FLI, PU.1) are involved in the regulation of a variety of genes in hematopoiesis; however despite this involvement, only ETV6 (also known as TEL) and FLI1 have been included on germline targeted sequencing panels for bleeding and platelet disorders and HM predisposition (1).