TP53 and embryonal rhabdomyosarcoma: One patient diagnosed with an anaplastic embryonal rhabdomyosarcoma (ERMS) at age 5 years, harbored a compound heterozygous genotype with two pathogenic TP53 variants in trans: the hotspot R248Q variant (MAF = 0.29) and a pathogenic splicing variant in intron 5 (MAF = 0.22).