Distribution of p53-effector lncRNAs across these categories of Hallmark processes (61) indicated a significantly higher number of lncRNAs negatively impacted/suppressed cancer cell proliferation (4-fold higher; FDR = 2.03 × 10−4; Wilcoxon rank-sum test) in cancer cells compared with the number of lncRNAs that positively impacted/induced the same processes (Supplementary Fig. S4). Here, TP53 is linked to cancer.