Importantly, using a previously published dataset (GEO accession: GSE54646; ref. 21), we found that the expression of CHAF1B is significantly upregulated in neutrophils isolated from patients with MPN with PV, ET, and PMF, when compared with neutrophils isolated from healthy donors (Fig. 2C). The gene discussed is CHAF1B; the disease is myeloproliferative disorder.