For example, IFNγ-inducible protein 30 (IFI30) is expressed in most antigen-presenting cells (APC), including monocytes, macrophages, and dendritic cells, where it functions in MHC class II-restricted antigen processing and has been shown to have a role in the immune response to malignant tumors such as melanoma, prostate cancer, and glioma (37–40). Here, IFI30 is linked to central nervous system cancer.