MIF and periodontitis: Transient but not permanent exposure of primary mouse or human fibroblasts with MIF significantly promoted wound closure, a response that encompassed both a proliferative and a pro-migratory component.33P. gingivaliswas found to contribute to the development of periodontitis via MIF.34 A study has compared the expression of MIF and CCL2/MCP-1 (Monocyte chemoattractant protein-1), one of the most studied chemokines, as it takes part in immune surveillance and immune modulation.