Improved Glucose Control with Weight Loss, Lower Insulin Doses, and no Increased Hypoglycemia with Empagliflozin Added to Titrated Multiple Daily Injections of Insulin in Obese Inadequately Controlled Type 2 Diabetes Diabetes Care Diabetes Care 2014 2014 37 37 7 7 1815 1815 1823 1823 10.2337/dc13-3055 10.2337/dc13-3055 24929430 24929430. This evidence concerns the gene INS and type 2 diabetes mellitus.