TNFRSF8 and classic Hodgkin lymphoma: In previous studies of CHL, the percentage of cases in which CD30 positivity in RSCs was reported ranged from 27% to 100% with 0 to 71% of cases lacking CD30 expression (Miettinen, 1992; Von Wasielewski et al., 1997; Rüdiger et al., 1998b; Watanabe et al., 2000; Salama et al., 2010; Ahmed et al., 2011; Paszkiewicz-Kozik et al., 2013).