Brentuximab vedotin is currently approved for CHL, anaplastic large cell lymphoma (ALCL) (another lymphoma where malignant cells uniformly express CD30), as well as CD30-expressing peripheral T-cell lymphomas and mycosis fungoides (MF) [ADCETRIS prescribing information]. This evidence concerns the gene TNFRSF8 and T-cell non-Hodgkin lymphoma.