Studies showed that the main anti-tumor mechanisms of this therapy were as follows: (1) gefitinib blocked the EGFR signaling pathway; (2) YAP-siRNA inhibited the activation of the EGFR bypass signaling pathway–YAP/MEK/ERK signaling pathway; and (3) photodynamic therapy induced the apoptosis of tumor cells [108]. The gene discussed is MAP2K7; the disease is neoplasm.