CCL2 and neoplasm: Furthermore, many other different molecules produced by tumor cells or by cells of the TME can induce MC chemotaxis, including CCL2 [105], CCL5 [106], CCL11 [106], CCL15 [102], CXCL12 [107], VEGF [80], FGF2 [108], osteopontin [109], and lipid mediators [103].