Finally, the variable wettability of the mats, as well as in their structural characteristics, showed an effect on the modulated release of the active agents and on their bioactivity, where the rapid release of Ag+ from the PSMA mats could see potential use in a dressing for a wound susceptible to infection, while PSMA@Tyr could be more suitable for a slow healing wound. This evidence concerns the gene FOLH1 and infection.