The published studies demonstrate that curcumin’s effects on PKM2 are not entirely conclusive: Sidiqqui et al. [161] demonstrated that curcumin decreases the PKM2 level at the level of mRNA and the protein in cell lines of different origin (H1299—non-small cell lung cancer; MCF7—breast cancer; HeLa—cervical cancer). The gene discussed is PKM; the disease is breast carcinoma.