In this field, a first insight related to curcumin was provided through discovery of its influence on the axis that includes hsa_circ_0007580 (circ-PRKCA), miR-384 and integrin subunit beta 1 (ITGB1) in the non-small cell lung cancer (NSCLC) model. The gene discussed is ITGB1; the disease is non-small cell lung carcinoma.