CD274 and nasopharyngeal carcinoma: Our lab employed our third-generation CAR NK92 cell line, which has been shown to target programmed cell death ligand-1 (PD-L1) and display improved cytotoxicity and apoptosis in various human cell lines that express PD-L1, in the NPC humanized mouse model in order to optimise the use of these cells in treating solid cancers and potentially induce their antitumour activity [70].