As described by our previous work, one of the pathways by which FA leads to Tau hyperphosphorylation is achieved by up-regulating the expression of glycogen synthase kinase-3β (GSK-3β) and calmodulin-dependent protein kinase II (CaMKII), both pivotal Tau kinases in AD, and down-regulating PP2A [30]. This evidence concerns the gene GSK3B and Alzheimer disease.