PTGS2 and ulcerative colitis: Comparably, Kim et al. [55] studied the protective effect of an ethanolic chickpea extract in a model of ulcerative colitis with DSS in mice, which suppressed the expression of pro-inflammatory interleukins, COX-2 and iNOS, potentially via the inactivation of NF-κB and activator of transcription 3 (STAT3).