CASP1 and multiple sclerosis: Interestingly, when comparing the cut-off points in this study for the inflammasome proteins caspase-1 (1.450 pg/mL), ASC (222.5 pg/mL), and IL-18 (159.5 pg/mL) with the cut-off points for the same proteins in patients with multiple sclerosis [61], we found that the inflammatory response contributed by the inflammasome was higher in patients with MS (caspase-1: 1.776 pg/mL, ASC: 537.5 pg/mL, IL-18: 238.2 pg/mL) [61] than in patients with PD.