The most prevalent PIP was the prescription of aspirin, clopidogrel, dipyridamole, vitamin K antagonists, direct thrombin inhibitors or factor Xa inhibitors with concurrent significant bleeding risk (i.e., severe uncontrolled hypertension, bleeding diathesis, recent non-trivial spontaneous bleeding), found in 23.98% patients and accounted for 29.50% of PIPs found, similar with other study results where this PIP was prevalent (19.4%) [22]. This evidence concerns the gene F10 and hypertensive disorder.